• Human spinal cord organoids exhibiting neural tube morphogenesis for a quantifiable drug screening system of neural tube defects

Ju-Hyun Lee, Hyogeun Shin, Mohammed R. Shaker, Hyun Jung Kim, June Hoan Kim, Namwon Lee, Minjin Kang, Subin Cho, Tae Hwan Kwak, Jong Woon Kim, Mi-Ryong Song, Seung-Hae Kwon, Dong Wook Han, Sanghyuk Lee, Se-Young Choi, Im Joo Rhyu, Hyun Kim, Dongho Geum, Il-Joo Cho, Woong Sun*

Nature Biomedical Engineering, in press (2022)

• Fluid shear stress regulates the landscape of microRNAs in endothelial cell-derived small extracellular vesicles and modulates the function of endothelial cells

Jihwa Chung, Kyoung Hwa Kim, Namhee Yu, Shung Hyun An, Sanghyuk Lee, Kihwan Kwon*

International Journal of Molecular Sciences, 23:1314 (2022)

• Comprehensive analysis of alternative splicing in gastric cancer identifies epithelial-mesenchymal transition subtypes associated with survival

Yukyung Jun, Yun-Suhk Suh, SungHee Park, Jieun Lee, Jong-Il Kim, Sanghyuk Lee, Wan-Ping Lee*, Olga Anczukow*, Han-Kwang Yang*, and Charles Lee*

Cancer Research, in press (2022)

• Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells

Gyu Jin Lee, Yukyung Jun, Yoon Kyung Jeon, Daekee Lee, Sanghyuk Lee*, Jaesang Kim*

Oncoimmunology, 11:(1), in press (2022)

• Nox4-IGF2 axis promotes differentiation of embryoid body cells into derivatives of the three embryonic germ layers

Jusong Kim, Jaewon Kim, Hee Jung Lim, Sanghyuk Lee, Yun Soo Bae*, Jaesang Kim*

Stem Cell Rev Rep., in press (2022)

• Proprotein convertase substlisin/kexin Type 9 is required for Ahnak-mediated metastasis of melanoma into lung epithelial cells

Jung Min Suh, Yelin Son, Jung-Yeon Yoo, Yookyung Goh, Nabil G Seidah, Sanghyuk Lee*, Yun Soo Bae*

Neoplasia, 23:993-1001 (2021)  

• FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress

Haeyeon Jang, Yukyung Jun, Suyeon Kim, Eunjeong Kim, Yeonjoo Jung, Byung Jo Park,  Jinseon Lee, Jhingook Kim, Sanghyuk Lee*, Jaesang Kim*

Cell Death & Disease, 12:407 (2021)

• Elucidating molecular mechanisms of acquired resistance to BRAF inhibitors in melanoma using a microfluidic device and deep sequencing

Jiyeon Han, Yeonjoo Jung, Yukyung Jun, Sungsu Park, Sanghyuk Lee*

Genomics & Informatics, 19(1):e2 (2021).

• Genome-scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib-resistant lung cancer

Jieun Lee, Ahyoung Choi, Sung-Yup Cho, Yukyung Jun, Deukchae Na, Ahra Lee, Giyong Jang, Jee Young Kwon, Jaesang Kim, Sanghyuk Lee*, Charles Lee* 

Molecular Oncology, 15(2):487-502 (2021)

• iCSDB: an integrated database of CRISPR screens

Ahyoung Choi, Insu Jang, Heewon Han, Min-Seo Kim, Jinhyuk Choi, Jieun Lee, Sung-Yup Cho, Yukyung Jun, Charles Lee, Jaesang Kim, Byungwook Lee*, Sanghyuk Lee*

Nucleic Acids Research, 49:D956-D961 (2021)